CHM01 Antibacterial Activity with Hummer's Method for Nano Graphene Oxide

Abstract

The current work describes how Schiff's reaction was used to create unique nanoparticles. Particularly, graphene oxide and hydrazine hydrate combined with astatine and guanine, respectively, to produce Schiff bases (II and III). On the other hand, graphite was added to a solution of sodium nitrate and strong sulfuric acid using Hummer's method, which also involves the use of oxidizing chemicals like hydrogen peroxide and potassium permanganate, to produce nanoparticle graphene oxide (I). A range of positive and negative gram bacteria were used to test the manufactured nanocomposite's biological activity using the Mueller-Hinton Agar well diffusion method. According to the research, the Nano Schiff base II exhibits an interesting inhibitory function, especially when it comes to Staphylococcus aureus germs.